Request BIGG reaction

request_bigg_universal_reaction(
  url = "http://bigg.ucsd.edu/api/v2/universal/reactions",
  reaction_id = "ADA",
  return_form = c("list", "data.frame")
)

Arguments

url

url http://bigg.ucsd.edu/api/v2/universal/reactions

reaction_id

reaction_id, for example, ADA

return_form

data.frame or list.

Value

universal metabolite information

Author

Xiaotao Shen shenxt1990@outlook.com

Examples

x <- request_bigg_universal_reaction(reaction_id = "ADA", return_form = "list")
x
#> $models_containing_reaction
#>              bigg_id
#> 1        iAB_RBC_283
#> 2            iAF1260
#> 3           iAF1260b
#> 4          iAM_Pb448
#> 5          iAM_Pc455
#> 6          iAM_Pf480
#> 7          iAM_Pk459
#> 8          iAM_Pv461
#> 9       iAPECO1_1312
#> 10       iAT_PLT_636
#> 11         iB21_1397
#> 12         iBWG_1329
#> 13           ic_1306
#> 14            iCHOv1
#> 15       iCHOv1_DG44
#> 16            iCN718
#> 17            iCN900
#> 18      iE2348C_1286
#> 19       iEC042_1314
#> 20         iEC1344_C
#> 21    iEC1349_Crooks
#> 22   iEC1356_Bl21DE3
#> 23         iEC1364_W
#> 24      iEC1368_DH5a
#> 25     iEC1372_W3110
#> 26     iEC55989_1330
#> 27      iECABU_c1320
#> 28         iECB_1328
#> 29        iECBD_1354
#> 30         iECD_1391
#> 31     iECDH10B_1368
#> 32       iEcDH1_1363
#> 33 iECDH1ME8569_1439
#> 34    iEcE24377_1341
#> 35       iECED1_1282
#> 36    iECH74115_1262
#> 37        iEcHS_1320
#> 38      iECIAI1_1343
#> 39     iECIAI39_1322
#> 40     iECNA114_1301
#> 41      iECO103_1326
#> 42      iECO111_1330
#> 43       iECO26_1355
#> 44       iECOK1_1307
#> 45       iEcolC_1368
#> 46         iECP_1309
#> 47         iECs_1301
#> 48       iECS88_1305
#> 49        iECSE_1348
#> 50        iECSF_1327
#> 51     iEcSMS35_1347
#> 52        iECSP_1301
#> 53       iECUMN_1333
#> 54         iECW_1372
#> 55           iEK1008
#> 56       iEKO11_1354
#> 57        iETEC_1333
#> 58       iG2583_1286
#> 59            iHN637
#> 60           iJN1463
#> 61            iJN746
#> 62           iJO1366
#> 63            iJR904
#> 64     iLB1027_lipid
#> 65        iLF82_1304
#> 66            iLJ478
#> 67           iML1515
#> 68           iMM1415
#> 69            iMM904
#> 70            iND750
#> 71            iNF517
#> 72            iNJ661
#> 73      iNRG857_1313
#> 74           iRC1080
#> 75           iS_1188
#> 76     iSbBS512_1146
#> 77         iSBO_1134
#> 78         iSDY_1059
#> 79          iSF_1195
#> 80         iSFV_1184
#> 81        iSFxv_1172
#> 82        iSSON_1240
#> 83      iUMN146_1321
#> 84      iUMNK88_1353
#> 85       iUTI89_1310
#> 86         iWFL_1372
#> 87         iY75_1357
#> 88           iYL1228
#> 89           iYS1720
#> 90            iYS854
#> 91           iZ_1308
#> 92            RECON1
#> 93           Recon3D
#> 94          STM_v1_0
#>                                                            organism
#> 1                                                      Homo sapiens
#> 2                         Escherichia coli str. K-12 substr. MG1655
#> 3                         Escherichia coli str. K-12 substr. MG1655
#> 4                                                Plasmodium berghei
#> 5                                     Plasmodium cynomolgi strain B
#> 6                                         Plasmodium falciparum 3D7
#> 7                                      Plasmodium knowlesi strain H
#> 8                                            Plasmodium vivax Sal-1
#> 9                                          Escherichia coli APEC O1
#> 10                                                     Homo sapiens
#> 11                                       Escherichia coli BL21(DE3)
#> 12                                          Escherichia coli BW2952
#> 13                                          Escherichia coli CFT073
#> 14                                               Cricetulus griseus
#> 15                                               Cricetulus griseus
#> 16                                      Acinetobacter baumannii AYE
#> 17                                     Clostridioides difficile 630
#> 18                           Escherichia coli O127:H6 str. E2348/69
#> 19                                             Escherichia coli 042
#> 20                                               Escherichia coli C
#> 21                                       Escherichia coli ATCC 8739
#> 22                                       Escherichia coli BL21(DE3)
#> 23                                               Escherichia coli W
#> 24                                      Escherichia coli DH5[alpha]
#> 25                         Escherichia coli str. K-12 substr. W3110
#> 26                                           Escherichia coli 55989
#> 27                                       Escherichia coli ABU 83972
#> 28                                   Escherichia coli B str. REL606
#> 29                        Escherichia coli 'BL21-Gold(DE3)pLysS AG'
#> 30                                       Escherichia coli BL21(DE3)
#> 31                         Escherichia coli str. K-12 substr. DH10B
#> 32                                             Escherichia coli DH1
#> 33                                             Escherichia coli DH1
#> 34                           Escherichia coli O139:H28 str. E24377A
#> 35                                            Escherichia coli ED1a
#> 36                             Escherichia coli O157:H7 str. EC4115
#> 37                                              Escherichia coli HS
#> 38                                            Escherichia coli IAI1
#> 39                                           Escherichia coli IAI39
#> 40                                           Escherichia coli NA114
#> 41                              Escherichia coli O103:H2 str. 12009
#> 42                              Escherichia coli O111:H- str. 11128
#> 43                              Escherichia coli O26:H11 str. 11368
#> 44                                         Escherichia coli IHE3034
#> 45                                       Escherichia coli ATCC 8739
#> 46                                             Escherichia coli 536
#> 47                              Escherichia coli O157:H7 str. Sakai
#> 48                                             Escherichia coli S88
#> 49                                            Escherichia coli SE11
#> 50                                            Escherichia coli SE15
#> 51                                         Escherichia coli SMS-3-5
#> 52                            Escherichia coli O157:H7 str. TW14359
#> 53                                          Escherichia coli UMN026
#> 54                                               Escherichia coli W
#> 55                                 Mycobacterium tuberculosis H37Rv
#> 56                                          Escherichia coli KO11FL
#> 57                                     Escherichia coli ETEC H10407
#> 58                              Escherichia coli O55:H7 str. CB9615
#> 59                                Clostridium ljungdahlii DSM 13528
#> 60                                        Pseudomonas putida KT2440
#> 61                                        Pseudomonas putida KT2440
#> 62                        Escherichia coli str. K-12 substr. MG1655
#> 63                        Escherichia coli str. K-12 substr. MG1655
#> 64                            Phaeodactylum tricornutum CCAP 1055/1
#> 65                                            Escherichia coli LF82
#> 66                                         Thermotoga maritima MSB8
#> 67                        Escherichia coli str. K-12 substr. MG1655
#> 68                                                     Mus musculus
#> 69                                   Saccharomyces cerevisiae S288C
#> 70                                   Saccharomyces cerevisiae S288C
#> 71                        Lactococcus lactis subsp. cremoris MG1363
#> 72                                 Mycobacterium tuberculosis H37Rv
#> 73                            Escherichia coli O83:H1 str. NRG 857C
#> 74                                        Chlamydomonas reinhardtii
#> 75                                  Shigella flexneri 2a str. 2457T
#> 76                                      Shigella boydii CDC 3083-94
#> 77                                            Shigella boydii Sb227
#> 78                                       Shigella dysenteriae Sd197
#> 79                                    Shigella flexneri 2a str. 301
#> 80                                    Shigella flexneri 5 str. 8401
#> 81                                        Shigella flexneri 2002017
#> 82                                            Shigella sonnei Ss046
#> 83                                           Escherichia coli UM146
#> 84                                          Escherichia coli UMNK88
#> 85                                           Escherichia coli UTI89
#> 86                                               Escherichia coli W
#> 87                         Escherichia coli str. K-12 substr. W3110
#> 88                Klebsiella pneumoniae subsp. pneumoniae MGH 78578
#> 89                                          Salmonella pan-reactome
#> 90               Staphylococcus aureus subsp. aureus USA300_TCH1516
#> 91                             Escherichia coli O157:H7 str. EDL933
#> 92                                                     Homo sapiens
#> 93                                                     Homo sapiens
#> 94 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
#> 
#> $bigg_id
#> [1] "ADA"
#> 
#> $old_identifiers
#> [1] "ADA{}ADNDA{}ADNDA_c"
#> 
#> $pseudoreaction
#> [1] "false"
#> 
#> $name
#> [1] "Adenosine deaminase"
#> 
#> $reaction_string
#> [1] "adn_c + h_c + h2o_c &#8652; ins_c + nh4_c"
#> 
#> $metabolites
#>   bigg_id      name compartment_bigg_id stoichiometry
#> 1     adn Adenosine                   c          -1.0
#> 2       h        H+                   c          -1.0
#> 3     h2o   H2O H2O                   c          -1.0
#> 4     ins   Inosine                   c           1.0
#> 5     nh4  Ammonium                   c           1.0
#> 
#> $database_link
#>                  database
#> 1                    RHEA
#> 2           KEGG Reaction
#> 3                  BioCyc
#> 4       Reactome Reaction
#> 5               EC Number
#> 6           SEED Reaction
#> 7 MetaNetX (MNX) Equation
#>                                                                                                                                                     id
#> 1                                                                                                                           24408{}24409{}24410{}24411
#> 2                                                                                                                                               R01560
#> 3                                                                                                                                 META:ADENODEAMIN-RXN
#> 4 R-BTA-5693346{}R-CFA-5693346{}R-DDI-5693346{}R-DME-5693346{}R-DRE-5693346{}R-GGA-5693346{}R-HSA-5693346{}R-SSC-5693346{}R-TGU-5693346{}R-XTR-5693346
#> 5                                                                                                                                              3.5.4.4
#> 6                                                                                                                                             rxn01137
#> 7                                                                                                                                            MNXR95432
#> 
y <- request_bigg_universal_reaction(reaction_id = "ADA", return_form = "data.frame")
y
#>   bigg_id     old_identifiers pseudoreaction                name
#> 1     ADA ADA{}ADNDA{}ADNDA_c          false Adenosine deaminase
#>                             reaction_string
#> 1 adn_c + h_c + h2o_c &#8652; ins_c + nh4_c
#>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         models_bigg_id
#> 1 iAB_RBC_283{}iAF1260{}iAF1260b{}iAM_Pb448{}iAM_Pc455{}iAM_Pf480{}iAM_Pk459{}iAM_Pv461{}iAPECO1_1312{}iAT_PLT_636{}iB21_1397{}iBWG_1329{}ic_1306{}iCHOv1{}iCHOv1_DG44{}iCN718{}iCN900{}iE2348C_1286{}iEC042_1314{}iEC1344_C{}iEC1349_Crooks{}iEC1356_Bl21DE3{}iEC1364_W{}iEC1368_DH5a{}iEC1372_W3110{}iEC55989_1330{}iECABU_c1320{}iECB_1328{}iECBD_1354{}iECD_1391{}iECDH10B_1368{}iEcDH1_1363{}iECDH1ME8569_1439{}iEcE24377_1341{}iECED1_1282{}iECH74115_1262{}iEcHS_1320{}iECIAI1_1343{}iECIAI39_1322{}iECNA114_1301{}iECO103_1326{}iECO111_1330{}iECO26_1355{}iECOK1_1307{}iEcolC_1368{}iECP_1309{}iECs_1301{}iECS88_1305{}iECSE_1348{}iECSF_1327{}iEcSMS35_1347{}iECSP_1301{}iECUMN_1333{}iECW_1372{}iEK1008{}iEKO11_1354{}iETEC_1333{}iG2583_1286{}iHN637{}iJN1463{}iJN746{}iJO1366{}iJR904{}iLB1027_lipid{}iLF82_1304{}iLJ478{}iML1515{}iMM1415{}iMM904{}iND750{}iNF517{}iNJ661{}iNRG857_1313{}iRC1080{}iS_1188{}iSbBS512_1146{}iSBO_1134{}iSDY_1059{}iSF_1195{}iSFV_1184{}iSFxv_1172{}iSSON_1240{}iUMN146_1321{}iUMNK88_1353{}iUTI89_1310{}iWFL_1372{}iY75_1357{}iYL1228{}iYS1720{}iYS854{}iZ_1308{}RECON1{}Recon3D{}STM_v1_0
#>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                models_bigg_organism
#> 1 Homo sapiens{}Escherichia coli str. K-12 substr. MG1655{}Escherichia coli str. K-12 substr. MG1655{}Plasmodium berghei{}Plasmodium cynomolgi strain B{}Plasmodium falciparum 3D7{}Plasmodium knowlesi strain H{}Plasmodium vivax Sal-1{}Escherichia coli APEC O1{}Homo sapiens{}Escherichia coli BL21(DE3){}Escherichia coli BW2952{}Escherichia coli CFT073{}Cricetulus griseus{}Cricetulus griseus{}Acinetobacter baumannii AYE{}Clostridioides difficile 630{}Escherichia coli O127:H6 str. E2348/69{}Escherichia coli 042{}Escherichia coli C{}Escherichia coli ATCC 8739{}Escherichia coli BL21(DE3){}Escherichia coli W{}Escherichia coli DH5[alpha]{}Escherichia coli str. K-12 substr. W3110{}Escherichia coli 55989{}Escherichia coli ABU 83972{}Escherichia coli B str. REL606{}Escherichia coli 'BL21-Gold(DE3)pLysS AG'{}Escherichia coli BL21(DE3){}Escherichia coli str. K-12 substr. DH10B{}Escherichia coli DH1{}Escherichia coli DH1{}Escherichia coli O139:H28 str. E24377A{}Escherichia coli ED1a{}Escherichia coli O157:H7 str. EC4115{}Escherichia coli HS{}Escherichia coli IAI1{}Escherichia coli IAI39{}Escherichia coli NA114{}Escherichia coli O103:H2 str. 12009{}Escherichia coli O111:H- str. 11128{}Escherichia coli O26:H11 str. 11368{}Escherichia coli IHE3034{}Escherichia coli ATCC 8739{}Escherichia coli 536{}Escherichia coli O157:H7 str. Sakai{}Escherichia coli S88{}Escherichia coli SE11{}Escherichia coli SE15{}Escherichia coli SMS-3-5{}Escherichia coli O157:H7 str. TW14359{}Escherichia coli UMN026{}Escherichia coli W{}Mycobacterium tuberculosis H37Rv{}Escherichia coli KO11FL{}Escherichia coli ETEC H10407{}Escherichia coli O55:H7 str. CB9615{}Clostridium ljungdahlii DSM 13528{}Pseudomonas putida KT2440{}Pseudomonas putida KT2440{}Escherichia coli str. K-12 substr. MG1655{}Escherichia coli str. K-12 substr. MG1655{}Phaeodactylum tricornutum CCAP 1055/1{}Escherichia coli LF82{}Thermotoga maritima MSB8{}Escherichia coli str. K-12 substr. MG1655{}Mus musculus{}Saccharomyces cerevisiae S288C{}Saccharomyces cerevisiae S288C{}Lactococcus lactis subsp. cremoris MG1363{}Mycobacterium tuberculosis H37Rv{}Escherichia coli O83:H1 str. NRG 857C{}Chlamydomonas reinhardtii{}Shigella flexneri 2a str. 2457T{}Shigella boydii CDC 3083-94{}Shigella boydii Sb227{}Shigella dysenteriae Sd197{}Shigella flexneri 2a str. 301{}Shigella flexneri 5 str. 8401{}Shigella flexneri 2002017{}Shigella sonnei Ss046{}Escherichia coli UM146{}Escherichia coli UMNK88{}Escherichia coli UTI89{}Escherichia coli W{}Escherichia coli str. K-12 substr. W3110{}Klebsiella pneumoniae subsp. pneumoniae MGH 78578{}Salmonella pan-reactome{}Staphylococcus aureus subsp. aureus USA300_TCH1516{}Escherichia coli O157:H7 str. EDL933{}Homo sapiens{}Homo sapiens{}Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
#>      metabolite_bigg_id                           metabolite_name
#> 1 adn{}h{}h2o{}ins{}nh4 Adenosine{}H+{}H2O H2O{}Inosine{}Ammonium
#>   metabolites_compartment_bigg_id  metabolites_stoichiometry
#> 1                   c{}c{}c{}c{}c -1.0{}-1.0{}-1.0{}1.0{}1.0
#>                 BioCyc EC_Number   KEGG  MetaNetX                       RHEA
#> 1 META:ADENODEAMIN-RXN   3.5.4.4 R01560 MNXR95432 24408{}24409{}24410{}24411
#>                                                                                                                                               Reactome
#> 1 R-BTA-5693346{}R-CFA-5693346{}R-DDI-5693346{}R-DME-5693346{}R-DRE-5693346{}R-GGA-5693346{}R-HSA-5693346{}R-SSC-5693346{}R-TGU-5693346{}R-XTR-5693346
#>       SEED
#> 1 rxn01137